Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-1 (of 1 Records) |
Query Trace: Sinden LL[original query] |
---|
Risk factors for diarrhea-associated infant mortality in the United States, 2005-2007
Mehal JM , Esposito DH , Holman RC , Tate JE , Sinden LL , Parashar UD . Pediatr Infect Dis J 2012 31 (7) 717-21 BACKGROUND: Diarrhea-associated deaths among US children increased from the mid-1980s through 2006, particularly among infants. Understanding risk factors for diarrhea-associated death could improve prevention strategies. METHODS: Records of singleton infants with diarrhea listed anywhere on the death certificate were selected from the US Linked Birth/Infant Death data for 2005-2007; characteristics of these infants were compared with those of infants who survived their first year. RESULTS: During 2005-2007, 1087 diarrhea-associated infant deaths were reported; 86% occurred among low birthweight (LBW, <2500 grams) infants. Compared with normal birthweight (NBW, ≥2500 grams) infants, LBW infants had a greater mortality rate (RR: 91.9, 95% CI: 77.4-109.0) and younger median age at death (7 versus 15 weeks, p<0.0001). The most common co-diagnoses for diarrhea-associated death among LBW and NBW infants were sepsis (26%) and volume depletion (20%), respectively. Among LBW infants, 97% of diarrhea-associated deaths occurred in inpatient settings, whereas 27% of NBW infant deaths occurred in outpatient settings and 5.3% in the decedent's home. Male sex, black race, unmarried status, and low 5-minute Apgar score (<7) increased mortality odds among LBW infants while, among NBW infants, low 5-minute Apgar score, black race, young maternal age (<25 years) and high birth order (third or more) increased mortality odds. CONCLUSIONS: Efforts to reduce diarrhea-associated morality should focus on understanding and improving management of diarrhea in vulnerable LBW infants. For prevention of diarrhea-associated deaths in NBW infants, educating mothers who fit the high risk profile regarding home hydration therapy and timely access to medical treatment is important. |
- Page last reviewed:Feb 1, 2024
- Page last updated:May 13, 2024
- Content source:
- Powered by CDC PHGKB Infrastructure